Symbol
Name
ID

Zbtb1
zinc finger and BTB domain containing 1
MGI:2442326

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

abnormal thymus morphology

thymus hypoplasia

decreased DN2 thymocyte number

decreased DN3 thymocyte number

decreased DN4 thymocyte number

abnormal B cell differentiation

decreased transitional stage B cell number

abnormal T cell differentiation

abnormal CD8-positive, alpha-beta T cell differentiation

decreased double-positive T cell number

decreased follicular B cell number

decreased B cell number

increased B cell number

decreased NK cell number

decreased CD4-positive, alpha-beta T cell number

increased central memory CD8 positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

Availability

Mouse Genotype

Zbtb1^m1Btlr/Zbtb1^m1Btlr

Zbtb1^m2Btlr/Zbtb1^m2Btlr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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